Serum triglyceride is an independent risk factor for acute coronary heart disease events in 35-64 years old Chinese-Chinese Multi-provincial Cohort Study
10.3321/j.issn:0253-3758.2008.10.019
- VernacularTitle:中国35～64岁人群血清甘油三酯与心血管病发病危险的关系
- Author:
Miao WANG
1
;
Dong ZHAO
;
Wei WANG
;
Jing LIU
;
Jun LIU
;
Sa LIU
;
Jia-Yi SUN
;
Lan-Ping QIN
;
Zhao-Su WU
Author Information
1. 首都医科大学附属北京安贞医院
- Keywords:
T riglyceride;
Acute coronary events;
Cohort study
- From:
Chinese Journal of Cardiology
2008;36(10):940-943
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the association between serum triglyeeride (TG) and the cardiovascular diseases (CVD) risk in Chinese population.Methods A total of 30,378 men and women aged 35-64 years old were recruited in the Chinese-Chinese Multi-provincial Cohort Study (CMCS).The serum TG and other CVD risk factors were measured.All subjects were followed up annually or biannually for acute CVD events from 1992 to 2004.A Cox regression model was established to identify the association between TG and risk of CVD events.Results The accumulative incidence rate of acute coronary heart disease (CHD) events increased from 62.6/100 000 in the low TG groups to 168.4/100 000 in the high TG group divided by the quartile.TG was identified as an independent risk factor for CHD after adjustment for the confounding risk factors by a Cox regression modeL Compared subjects with TG＜0.81 mmol/L,CHD risk increased 81% and 59% in subjects with TG 1.15-1.59 mmol/L and TG≥1.60 mmol/L,respectively (all P＜0.05).There was no significant association between TG level and the risks of hemorrhagic and iachemie stroke events (P＞0.05).Conclusion Serum TG is an independent risk factor for acute CHD events in Chinese population aged 35-64.
