Effects of shugan jianpi gusui recipe on multiple sclerosis recurrence: a primary report.
- Author:
Yu-Qian ZHOU
1
;
Wen-Qin MAO
;
Xiao-Jun ZHANG
;
Tao LI
Author Information
- Publication Type:Journal Article
- MeSH: Adrenal Cortex Hormones; therapeutic use; Adult; Azathioprine; therapeutic use; Drugs, Chinese Herbal; therapeutic use; Humans; Middle Aged; Multiple Sclerosis; drug therapy; Recurrence; gamma-Globulins; therapeutic use
- From: Chinese Journal of Integrated Traditional and Western Medicine 2013;33(1):31-34
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effects of Shugan Jianpi Gusui Recipe (SJGR) on multiple sclerosis (MS).
METHODSA case cohort study was used. The MS patients were assigned to the test group (14 cases) and the control group (21 cases) according to whether they would combine with Chinese herbs. Corticosteroids or gamma globulin was administered to all patients in the acute phase. SJGR was administered to patients in the test group in the remission phase, while those in the control group were not treated or treated by azathioprine alone. They were followed-up for a long time after their first visits. The observation time ranged 10-131 successive months. The recurrence intervals and the yearly average recurrence times were calculated in the two groups.
RESULTSWhen compared with before treatment, the recurrence interval was obviously prolonged, and the yearly average recurrence times decreased in the test group after treatment with statistical difference (P < 0.05). There was statistical difference in the recurrence interval and the yearly average recurrence times between the test group and the control group (P < 0.05).
CONCLUSIONSSJGR showed better effects in prolonging the recurrence interval and reducing the yearly average recurrence times of MS patients. It is worth further researches.
