High central pulse pressure level is associated with cardiovascular disease in patients receiving maintenance peritoneal dialysis.
- Author:
Xiaobing YANG
1
;
Dongfeng GUO
;
Jianping JIANG
Author Information
- Publication Type:Journal Article
- MeSH: Blood Pressure; Cardiovascular Diseases; physiopathology; Cross-Sectional Studies; Humans; Peritoneal Dialysis; Risk Factors
- From: Journal of Southern Medical University 2015;35(5):716-719
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the association between central pulse pressure level and cardiovascular diseases (CVD) in patients receiving maintenance peritoneal dialysis.
METHODSThis cross-sectional study was conducted in 234 patients on maintenance peritoneal dialysis. Central pulse pressure levels were measured using a SphygmoCor analyzer, and cardiovascular diseases were defined as diagnosed ischemic heart disease, heart failure, stroke or peripheral vascular disease.
RESULTSThe central pulse pressure levels of patients with CVD were significantly higher than those without CVD (51.7 ± 22.5 vs 43.7 ± 17.8 mmHg, P=0.004), while the brachial pulse pressure levels were comparable between the two patient groups. After adjusting for brachial pulse pressure and other relevant risk factors, central pulse pressure level was found to independently associate with CVD (adjusted OR=1.33, 95% CI 1.01-1.73, P=0.04 ).
CONCLUSIONHigh central pulse pressure level may serve as a risk factor for CVD in patients on maintenance peritoneal dialysis.
