Correlation between IL-6 levels and polymerized human serum albumin ceptor (PHSAR) in serum of chronic hepatitis patients.
- Author:
Zhiqing LI
1
;
Ruiquan WEI
;
Boquan JIN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Hepatitis B virus; physiology; Hepatitis B, Chronic; blood; Humans; Interleukin-6; blood; Middle Aged; Receptors, Albumin; blood; Virus Replication
- From: Chinese Journal of Experimental and Clinical Virology 2002;16(1):33-36
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUNDTo investigate the relationship between interleukin-6 (IL-6) levels in serum and HBV replication and the role of IL-6 in liver damage in chronic hepatitis B patients.
METHODSDetected IL-6 levels and polymerized human serum albumin receptor (PHSA-R) in serum of different type of HBV markers positive patients and of different degree of chronic hepatitis B patients.
RESULTSThe results showed that the serum IL-6 levels were increased significantly in PHSA-R positive patients than in PHSA-R negative patients in chronic hepatitis B (P<0.01). The serum IL-6 levels were correlated with the levels of PHSA-R (r=0.694, P<0.01), and the degree of symptoms.
CONCLUSIONSThis study suggested that the IL-6 levels in serum of hepatitis B patients correlated HBV replication and the degree of liver damage, serum IL-6 levels may be used as a value indicating of HBV replication, the degree of symptoms and the effect of treatment.
