Therapeutic effects of three topical remedies on periodontitis.
- Author:
Xiao-you FU
1
;
Guo-feng LI
Author Information
- Publication Type:Journal Article
- MeSH: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; administration & dosage; therapeutic use; Female; Humans; Iodine; agonists; therapeutic use; Male; Metronidazole; administration & dosage; therapeutic use; Middle Aged; Minocycline; administration & dosage; therapeutic use; Periodontal Pocket; Periodontitis; drug therapy; Young Adult
- From: Journal of Southern Medical University 2010;30(3):611-613
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo compare the therapeutic effects of minocycline, metronidazole and iodine glycerin on periodontitis.
METHODSA total of 123 patients were randomly divided into 3 groups to receive the 3 topical remedies administered into the periodontal pockets. The total response rate of the 3 treatments was calculated, and the changes in GI, PL I, PD and BO P were observed.
RESULTSAll the clinical indices of the 3 groups showed obvious improvements after the treatments compared with the baseline levels. The clinical indices of minocycline group and metronidazole group showed significant greater improvements than those of iodine glycerin group. The total response rate in minocycline group and metronidazole group was higher than that of iodine glycerin group.
CONCLUSIONSMinocycline and metronidazole as topical remedies can be effective auxiliary treatments of periodontitis.
