Traditional Chinese and Western medicine treatment of mycoplasmal pneumonia in children and the serum cytokine changes.
- Author:
Di-jun LIU
1
;
Bin ZHENG
;
Bao-huan CAI
;
Wang-mei ZHOU
;
Bi-xiang YU
Author Information
- Publication Type:Journal Article
- MeSH: Azithromycin; therapeutic use; Child; Child, Preschool; Cytokines; blood; Drug Therapy, Combination; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Infant; Male; Phytotherapy; Pneumonia, Mycoplasma; blood; drug therapy; Treatment Outcome
- From: Journal of Southern Medical University 2010;30(3):626-630
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the therapeutic effect of traditional Chinese medicine (TCM) and Western medicine (WM) treatments on mycoplasmal pneumonia in children and the changes in the serum cytokines.
METHODSNinety children with mycoplasmal pneumonia were randomly divided into the treatment group and the control group. TCM was given orally and azithromycin at the daily dose of 10 mg/kg was administered intravenously in the treatment group. In the control group, only intravenous azithromycin was given. After a 7-day treatment, the response rate, time of symptom disappearance, and serum levels of IL-6, IL-8 and TNF-alpha were observed.
RESULTSThe total response rate was 93.33% in the treatment group and 73.33% in the control group, showing a significantly better therapeutic effect in the treatment group (P<0.05). The combined treatments also showed better effects in alleviating fever, coughing and rales (P<0.05), and resulted in more obvious reduction in the serum levels of cytokines (P<0.05).
CONCLUSIONCombined treatment with TCM and WM produce good therapeutic effects in children with mycoplasmal pneumonia.
