Detection of Human Herpesvirus-6 DNA in Peripheral Blood Cells of Patients with Myelogenous Leukemia by Nested PCR
- Author:
Yuhong LU
1
;
Yubing ZHOU
;
Shaohua CHEN
;
Lijian YANG
;
Yangqiu LI
Author Information
1. Division of Hematology of the First Affiliated Hospital, Department of Biochemistry, Department of Hematology, Jinan Univerity Medical College, Guangzhou 510630, China.
- Publication Type:Journal Article
- From:
Journal of Experimental Hematology
2000;8(3):189-191
- CountryChina
- Language:Chinese
-
Abstract:
Human herpesvirus-6 (HHV-6) is largly disseminated in human population, which may relate to many diseases. Due to different methods previously used, the results of HHV-6 DNA detections in patients with leukemia are not identical. With a control-study, HHV-6 DNA in the blood cells from 38 cases, including 30 cases with acute myeloid leukemia and 8 cases with chronic myelogenous leukemia was detected by nested PCR. The results showed that HHV-6 DNA positive rate (63%) in patients with AML was lower than that in controls, whereas no significant difference between patients with CML (75%) and controls (92%) was shown. The clinical importance of HHV-6 infections in myelogenous leukemia should continue to be investigated later.
