Progress in Study on MHC Structure and Function
- Author:
Yuying SUN
1
;
Fanhua KONG
;
Yongzhi XI
Author Information
1. Department of Immunology, Beijing Beitaiping Rood Hospital, Beijing 100039, China.
- Publication Type:Journal Article
- From:
Journal of Experimental Hematology
2000;8(3):227-230
- CountryChina
- Language:Chinese
-
Abstract:
The MHC molecules were first discovered as major histocompatibility antigens. When their essential biological function as antigen-binding molecules and informers for T cells was unveiled, an explanation of why MHC also acts as major histocompatibility antigens was provided. When the antigen-binding cleft of MHC molecules was firstly clarified more than 10 years ago, the study of MHC structure and function has stepped into a prosperous new era, and many achievements have in this area have been achieved. This paper summarized the exciting progress in study on MHC structure and function in recent years.