Epilepsy and Oxidative Stress.
- Author:
Won Seop KIM
1
Author Information
1. Department of Pediatrics, Chungbuk National University College of Medicine, Cheongju, Korea. wskim@chungbuk.ac.kr
- Publication Type:Review
- Keywords:
Epilepsy;
Oxidative stress;
Neuronal death;
Mitochondri
- MeSH:
Brain;
Epilepsy*;
Mitochondrial Diseases;
Neurons;
Oxidative Phosphorylation;
Oxidative Stress*
- From:Journal of Korean Epilepsy Society
2004;8(2):103-107
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Epilepsy is arising from many molecular and biochemical events. In the underlying mechanisms of epilepsy, oxidative stress plays an important role in seizure-induced brain damage and neuronal death. Also epileptic seizures are noted in mitochondrial diseases with problems in oxidative phosphorylation. So oxidative stress is an important emerging cause of seizure-induced neuronal death as well as a result of epileptic seizure event.