Complex Partial Seizure Like Symptoms Presented by a Patient with Insulinoma and Hyperproinsulinemia.
- Author:
Young Rok DO
1
;
Oh Dae KWON
;
Ji Eun KIM
;
Jin Kuk DO
;
Dong Kuck LEE
Author Information
1. Department of Neurology, School of Medicine, Catholic University of Daegu, Daegu, Korea. dolbaeke@cu.ac.kr
- Publication Type:Case Report
- Keywords:
Insulinoma;
Complex partial seizure;
Proinsulin
- MeSH:
Adenoma, Islet Cell;
Adult;
Amnesia;
Blood Glucose;
Diagnosis;
Epilepsy;
Growth Hormone;
Humans;
Insulin;
Insulinoma*;
Proinsulin;
Psychotic Disorders;
Rare Diseases;
Seizures*;
Tomography, X-Ray Computed;
Vital Signs
- From:Journal of Korean Epilepsy Society
2004;8(2):167-170
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Insulinoma with hyperproinsulinemia and normal serum insulin level is a rare disease. Because of the neuroglycopenic symptoms, the initial diagnosis tends to be made as epilepsy or as psychosis. A 43-year-old man was admitted to our hospital because of recurrent confusional episodes. Symptoms are intermittent and consist of staring, confusion, amnesia, and bizarre behavior. Vital signs during the episode were normal but the serum glucose level was 27 mg/dl. The serum level of insulin during the episode was lower than normal and those of proinsulin and growth hormone were higher than normal. Solitary pancreatic mass was found by abdominal CT, measuring 15 mm in diameter. Pathologic evaluation showed islet cell tumor. This suggests that the serum level of proinsulin should be checked when insulinoma with neuroglycopenic symptom is suspected.
