Sulfur-containing amides from Entada phaseoloides.
- Author:
Hui XIONG
1
;
Er XIAO
;
Ying-Hong ZHAO
;
Guang-Zhong YANG
;
Zhi-Nan MEI
Author Information
1. College of Pharmacy, South-Central University for Nationalities, Wuhan 430074, China.
- Publication Type:Journal Article
- MeSH:
Acrylamides;
chemistry;
isolation & purification;
Fabaceae;
chemistry;
Molecular Structure;
Plants, Medicinal;
chemistry;
Seeds;
chemistry;
Thioglucosides;
chemistry;
isolation & purification
- From:
Acta Pharmaceutica Sinica
2010;45(5):624-626
- CountryChina
- Language:English
-
Abstract:
To study the chemical constituents of the Entada phaseoloides (L.) Merr., seeds of Entada phaseoloides were extracted with 70% ethanol at room temperature. Isolation and purification were performed by silica gel, reversed-phase silica gel column chromatography and semi-preparative HPLC. Structures of the pure compounds were established on the basis of spectral analysis. Four sulfur-containing amide compounds were isolated from the n-BuOH-soluble fraction and identified as entadamide A-beta-D-glucopyranosyl-(1-->3)-beta-D-glucopyranoside (1), entadamide A (2), entadamide A-beta-D-glucopyranoside (3) and clinacoside C (4). Compound 1 is a new compound. Compound 4 is isolated from the genus Entada for the first time.
