A quantitation method for andrographolide and dehydroandrographolide by X-ray powder diffraction Fourier fingerprint pattern technique.
- Author:
Ning-Bo GONG
1
;
Li-Juan LÜ
;
Chao LIU
;
Lin MA
;
Ruo-Yun CHEN
;
Yang LÜ
Author Information
1. Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
- Publication Type:Journal Article
- MeSH:
Andrographis;
chemistry;
Chromatography, High Pressure Liquid;
Diterpenes;
analysis;
Drugs, Chinese Herbal;
analysis;
Fourier Analysis;
Plant Components, Aerial;
chemistry;
Plants, Medicinal;
chemistry;
Powders;
X-Ray Diffraction;
methods
- From:
Acta Pharmaceutica Sinica
2010;45(5):673-676
- CountryChina
- Language:Chinese
-
Abstract:
The powder X-ray diffraction Fourier fingerprint pattern technique was used to develop a new quantitation method for the analysis of andrographolide and dehydroandrographolide. And the high performance liquid chromatography method was used to evaluate the quantity of andrographolide and dehydroandrographolide. The relationship of diffraction peak intensity and content of andrographolide and dehydroandrographolide was investigated. The powder X-ray diffraction Fourier fingerprint pattern analysis technique can be used to evaluate the quantity of andrographolide and dehydroandrographolide in the herb simultaneously.
