Alkaloids from the leaves of Nauclea officinalis.
- Author:
Long FAN
1
;
Chun-Lin FAN
;
Ying WANG
;
Xiao-Qi ZHANG
;
Qing-Wen ZHANG
;
Jun-Qing ZHANG
;
Wen-Cai YE
Author Information
1. Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China.
- Publication Type:Journal Article
- MeSH:
Alkaloids;
chemistry;
isolation & purification;
Camptothecin;
analogs & derivatives;
chemistry;
isolation & purification;
Indole Alkaloids;
chemistry;
isolation & purification;
Indoles;
chemistry;
isolation & purification;
Molecular Structure;
Plant Leaves;
chemistry;
Plants, Medicinal;
chemistry;
Rubiaceae;
chemistry;
Vinca Alkaloids;
chemistry;
isolation & purification
- From:
Acta Pharmaceutica Sinica
2010;45(6):747-751
- CountryChina
- Language:Chinese
-
Abstract:
To study chemical constituents of the leaves of Nauclea officinalis, eight alkaloids were isolated from 95% ethanol extract by various chromatographic methods. The structures were elucidated on the basis of spectroscopic data (IR, UV, ESI-MS, 1D and 2D NMR) and identified as naucleactonin C (1), strictosamide (2), vincosamide (3), pumiloside (4), angustoline (5), angustine (6), 18, 19-dihydroangustine (7) and naucleofficine D (8). Compound 1 is a new indole alkaloid. Compounds 6 and 7 were isolated from this plant for the first time.
