The post-injury regenerating ability of temporomandibular joint of rats exposed to the repeated + Gz forces.
- Author:
Liang MA
1
;
Min HU
;
Zhen-yu SUN
;
Hua CHEN
;
Chun-hai LI
;
Zhong-chen XIE
Author Information
- Publication Type:Journal Article
- MeSH: Acceleration; adverse effects; Animals; Male; Rats; Rats, Wistar; Temporomandibular Joint; injuries; pathology; ultrastructure
- From: Chinese Journal of Stomatology 2006;41(6):364-367
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the post-injury regenerating ability of temporomandibular joint of rats exposed to the repeated + Gz forces.
METHODSOne hundred and eight male rats were randomly assigned to 9 groups, with 12 rats in each group. Group A was normally fed serving as the blank control group. Group B was only fixed with rat-kept devices for 5 minutes as the fixed control group. Group C was borne +1 Gz for 5 minutes. In the same position as group C, group D, E, F, G, H and I were repeatedly exposed to +10 Gz for 30 seconds each time with 5 times a day and +1 Gz for 1 minutes as a interval. The 6 groups were treated in the condition above for 4 days a week and 4 weeks in total. The rats in group A, B, C and D were killed on the next day after the centrifuge. The rats in group E, F, G, H and I were killed at 1, 2, 4, 8 and 12 weeks after the centrifuge, respectively. After the rats were killed, temporomandibular joint were taken for observation under optical microscope, scanning electron-microscope (SEM) and transmission electron-microscope (TEM).
RESULTSThere was no significant difference observed in group A, B and C. But in group D, E, F, G, H and I pathologic injuries and self-regeneration were seen in TMJ in different degrees.
CONCLUSIONSThe injury of TMJ could regenerate gradually with time.
