Ultrasound-mediated gene delivery.
- Author:
Wei HE
1
;
Rui LIU
;
Yazhu CHEN
;
Yuhong XU
Author Information
1. College of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai 200030, China.
- Publication Type:Journal Article
- MeSH:
DNA;
administration & dosage;
Drug Delivery Systems;
Gene Transfer Techniques;
instrumentation;
Genetic Therapy;
Humans;
Microbubbles;
Transfection;
methods;
Ultrasonic Therapy;
methods;
Ultrasonics
- From:
Journal of Biomedical Engineering
2005;22(2):403-406
- CountryChina
- Language:Chinese
-
Abstract:
Recently there have been increasing interests in ultrasound-mediated gene delivery techniques. This paper reviews the general concept of sonoporation, the effect of contrast agents, and the in vitro and in vivo applications of such techniques. Factors which contribute to the efficiency of gene delivery were also discussed. The technology is promising and has great potential in targeted drug delivery and gene delivery applications.
