One new lignan glycoside from whole plants of Senecio chrysanthemoides.
- Author:
Sheng LIN
1
;
Zhongxiao ZHANG
;
Yunheng SHEN
;
Huiliang LI
;
Lei SHAN
;
Runhui LIU
;
Xike XU
;
Weidong ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography; methods; Glycosides; chemistry; isolation & purification; Lignans; chemistry; isolation & purification; Plant Extracts; chemistry; Plants, Medicinal; chemistry; Senecio; chemistry
- From: China Journal of Chinese Materia Medica 2011;36(13):1755-1762
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the chemical constituents from the whole plants of Senecio chrysanthemoides.
METHODConstituents were isolated by using a combination of various chromatographic techniques including column chromatography over silica gel, Sephadex LH-20, and ODS C18, as well as reversed-phase HPLC. Structures of the isolates were identified by spectroscopic and chemical methods.
RESULTEighteen glycosides were obtained from a H2O-soluble portion of an ethanolic extract of the whole plants of Senecio chrysanthemoides and their structures were elucidated as 5'-methoxyligusinenoside B (1), hyuganoside III b (2), citrusin A (3), alaschanioside A (4), citrusin B (5), dehydrodieoniferyl alcohol 4, gamma'-di-O-beta-D-glucopyranoside (6), osmanthuside G (7), syringin (8), dehydrosyringin (9), 2-(4-hydroxy-3,5-dimethoxyphenyl) ethanol 4-O-beta-D-glucopyranoside (10), 2-phenylethyl beta-gentiobioside (11), phenethyl beta-D-glucopyranoside (12), nikoenoside (13), benzyl beta-D-glucopyranoyl (1 --> 6 ) -beta-D-glucopyranoside (14), 3,5-dimethoxy-4-hydroxybenzyl alcohol 4-O-beta-D-glucopyranoside (15), icariside B2 (16), sonchuionoside C (17), and 1-[(beta-D-glucopyranosyloxy) methyl] -5,6-dihydropyrrolizin-7-one (18).
CONCLUSIONCompound 1 was a new lignan glycoside, and the remaining compounds were obtained from this plant for the first time.
