Research progress of identifying predictive biomarkers for induction therapy in esophageal cancer.
- Author:
Yao LIN
1
;
Keneng CHEN
Author Information
1. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department One of Thoracic Surgery, Peking University School of Oncology, Peking University Cancer Hospital and Institute, Beijing 100142, China. chenkeneng@bjmu.edu.cn.
- Publication Type:Journal Article
- MeSH:
Biomarkers;
Chemoradiotherapy;
Esophageal Neoplasms;
drug therapy;
Humans;
Neoadjuvant Therapy;
Survival Rate
- From:
Chinese Journal of Gastrointestinal Surgery
2015;18(9):953-957
- CountryChina
- Language:Chinese
-
Abstract:
Surgery is still the major treatment for esophageal cancer. It remains controversial, whether induction radiochemotherapy before resection can improve long-term survival for esophageal cancer patients. Researches have found that preoperative treatment only increases survival rates for patients who respond to induction therapy, but not for non-responders. Therefore, to identify the predictive biomarkers for induction therapy draw much attention. Although still far from satisfactory results, some have been obtained. Here, we summarize the potential biomarker candidates for reference.
