Diterpenes constituents of Tripterygium wilfordii.
- Author:
Sui LIN
1
;
Xian-Yong YU
;
Hui-Qing QUE
;
Zhong CHEN
;
Di-Lin XIE
;
Yuan-Chao LI
Author Information
- Publication Type:Journal Article
- MeSH: Diterpenes; chemistry; isolation & purification; Molecular Structure; Plant Roots; chemistry; Plants, Medicinal; chemistry; Tripterygium; chemistry
- From: Acta Pharmaceutica Sinica 2005;40(7):632-635
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo study the chemical constituents of Tripterygium wilfordii Hook. F.
METHODSVarious column chromatographies with silica gel were used for the isolation and purification. The structures of compounds were established on the basis of its IR, MS, UV, 1H NMR, 13C NMR and HRMS, 1H-1H COSY, 1H-13C COSY and NOESY.
RESULTSFour diterpenoids were isolated: 16-hydroxytriptolide (I), triptolidenol (II), tripdiolide (III), 2-epitripdiolide (IV).
CONCLUSIONCompound IV is a new diterpenoid.
