Limonoids from fruits of Melia toosendan.
- Author:
Qiong ZHANG
1
;
Qing-Shan LI
;
Jing-Yu LIANG
;
Zhi-Da MIN
Author Information
1. Department of Pharmaceutical Science, Shanxi Medical University, Taiyuan 030001, China. zhangqiong_83@hotmail.com
- Publication Type:Journal Article
- MeSH:
Fruit;
chemistry;
Limonins;
chemistry;
isolation & purification;
Melia;
chemistry;
Molecular Structure;
Plants, Medicinal;
chemistry
- From:
Acta Pharmaceutica Sinica
2010;45(4):475-478
- CountryChina
- Language:Chinese
-
Abstract:
To study the chemical constituents of the fruits of Melia toosendan, three limonoids were isolated and purified by repeated silica gel column chromatography and preparative HPLC from the EtOAc extract of M. toosendan. Their structures were determined by their physico-chemical properties and spectroscopic data (1D-NMR, 2D-NMR) as: 24, 25, 26, 27-tetranorapotirucalla-(apoeupha)-1alpha-tigloyloxy-3alpha, 7alpha-dihydroxyl-12alpha-acetoxyl-14, 20, 22-trien-21, 23-epoxy-6, 28-epoxy (1), nimbolinin B (2), and trichilinin D (3), separately. Compound 1 is a new compound, and compound 2 is obtained from this plant for the first time.
