Isolation and identification of chemical constituents from Taxus cuspidta Sibe et Zucc.
- Author:
Di WU
1
;
Ya-Nan LI
;
Li-Jun WU
;
Hui-Yuan GAO
Author Information
1. The Liaoning Provincial Public Security Office, Shenyang 110032, China.
- Publication Type:Journal Article
- MeSH:
Azulenes;
chemistry;
isolation & purification;
Coumarins;
chemistry;
isolation & purification;
Inositol;
analogs & derivatives;
chemistry;
isolation & purification;
Molecular Structure;
Plants, Medicinal;
chemistry;
Taxoids;
chemistry;
isolation & purification;
Taxus;
chemistry
- From:
Acta Pharmaceutica Sinica
2010;45(11):1398-1401
- CountryChina
- Language:Chinese
-
Abstract:
Three compounds were isolated from the extract of Taxus cuspidta Sibe et Zucc with the column chromatography on silica gel and preparative HPLC methods. Their structures were identified according to the physicochemical properties and spectral analysis, and they were identified as (E)-1-methoxy-2-O-(p-coumaroyl)-myo-inositol (1), 2-deacetoxy-7beta, 9a, 10beta-trideacetyltaxinine J (2) and (3aS, 4aR, 6S, 8S, 8aS, 9R, 10R, 10aS)-benz[f]azulene-6, 8, 9, 10 (3H)-terol, 3a, 4, 4a, 5, 6, 7, 8, 8a, 9, 10-decahydro-10a-(1-hydroxyl-1-methylethyl)-1, 8a-dimethyl-5-methylene (3). Among them, compound 1 was a new compound, and compounds 2, 3 were two novel natural products.
