The research practice of anti-arrhythmic agents targeting on potassium ion channel.
- Author:
Qian YANG
1
;
Xiao-Jian WANG
;
Yi-Qun TANG
;
Qi-Dong YOU
Author Information
1. Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
- Publication Type:Journal Article
- MeSH:
Amiodarone;
analogs & derivatives;
chemistry;
pharmacology;
therapeutic use;
Animals;
Anti-Arrhythmia Agents;
chemistry;
pharmacology;
therapeutic use;
Arrhythmias, Cardiac;
drug therapy;
physiopathology;
Humans;
Hydantoins;
Imidazolidines;
chemistry;
pharmacology;
therapeutic use;
Molecular Structure;
Piperazines;
chemistry;
pharmacology;
therapeutic use;
Potassium Channel Blockers;
pharmacology;
therapeutic use;
Potassium Channels;
drug effects
- From:
Acta Pharmaceutica Sinica
2011;46(1):12-18
- CountryChina
- Language:Chinese
-
Abstract:
Due to the complicated pathogenesis of cardiac arrhythmia, the safe and effective therapeutic strategies for cardiac arrhythmia remain an urgent medical problems in the recent years. In this paper, we introduced the research practice of anti-arrhythmic agents targeting on potassium ion channel. The research progress of anti-arrhythmic agents in up-to-date literatures were also reviewed and prospected.
