Application of small molecule compounds inducing differentiation of stem cells.
- Author:
Xia LI
1
;
Lei SHAN
;
Wen-lin LI
;
Shou-de ZHANG
;
Wei-dong ZHANG
Author Information
1. Department of Medicinal Chemistry of Natural Product, School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Cell Differentiation;
drug effects;
Drugs, Chinese Herbal;
isolation & purification;
pharmacology;
Embryonic Stem Cells;
cytology;
High-Throughput Screening Assays;
methods;
Humans;
Plants, Medicinal;
chemistry;
Regenerative Medicine;
trends;
Signal Transduction;
Small Molecule Libraries;
chemistry;
pharmacology;
Stem Cells;
cytology;
Wnt Proteins;
metabolism
- From:
Acta Pharmaceutica Sinica
2011;46(2):121-126
- CountryChina
- Language:Chinese
-
Abstract:
With the development of stem cells and regenerative medicine (treatment of various diseases using stem cells) research, the induction of differentiation of human stem cell technology has also made significant progress. The development of chemical biology offers a variety of small biological molecules for stem cell biology. This review focuses on how small molecule compounds (natural and synthetic) induce differentiation of stem cells.
