Comprehensive analysis of relevant factors on colorectal cancer-related anemia.
- Author:
Jun-Na GE
1
;
Jian-Chun YU
;
Wei-Ming KANG
;
Zhi-Qiang MA
;
Ying-Chao GU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Anemia; etiology; Colorectal Neoplasms; complications; Female; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors
- From: Acta Academiae Medicinae Sinicae 2011;33(5):549-554
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the risk factors of colorectal cancer-related anemia.
METHODThe clinical data of 319 patients with colorectal cancer were retrospectively analyzed for the possible risk factors of tumor-related anemia including tumor location, clinical stage, clinical symptoms, pathology, gender, and age.
RESULTSOf these 319 cases, 141 (44.20%) had anemia. The incidence of anemia was 62.20% among patients with right hemicolon cancers (including caecum cancer), and was 23.82% among patients with rectal cancer and 36.23% among those with transverse descending or sigmoid colon cancer. Cardia insufficiency, melena, tumor location, T staging, hypoproteinemia were also found to be related with anemia. Anemia and hypoproteinemia were the risk factors for perioperative blood transfusion (odds ratio = 3.004, odds ratio = 8.356, respectively).
CONCLUSIONSThe colorectal cancer-related anemia is not associated with the clinical stage of the tumor, while cardiac insufficiency, melena, tumor location, tumor stage, and hypoproteinemia constitute the possible risk factors. Anemia and hypoproteinemia are the risk factors of perioperative blood transfusion.
