Clinical and imaging manifestations of pulmonary mucosa-associated lymphoid tissue lymphoma.
- Author:
Xin SUI
1
;
Wei SONG
;
Zheng-Yu JIN
;
Rui-E FENG
;
Quan-Cai CUI
;
Hua-Dan XUE
;
Shuo LI
;
Hao SUN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Female; Humans; Lung Neoplasms; diagnosis; diagnostic imaging; pathology; Lymphoma, B-Cell, Marginal Zone; diagnosis; diagnostic imaging; pathology; Male; Middle Aged; Radiography; Retrospective Studies
- From: Acta Academiae Medicinae Sinicae 2012;34(1):41-45
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical and computed tomography (CT) appearances of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma.
METHODSThe CT findings and clinical data of 13 patients with pathologically proven pulmonary MALT lymphoma were retrospectively reviewed.
RESULTSAmong these 13 patients, seven presented no notable abnormalities, six manifested respiratory symptoms including cough, expectoration, and dyspnea; one of these six patients experienced fever. Chest CT showed solitary nodule in 2 patients and multiple nodules in 3 patients; meanwhile, it showed solitary consolidation in 3 patients and multiple consolidations in 5 patients. Other CT findings included air bronchogram (n = 13), airway dilatation (n = 4), ground glass opacities (n = 5), and interstitial changes (n = 5). One patient had mediastinal lymphoadenopathy and 2 had pleural effusion. Pathology showed massive lymphocyte infiltration; cells with notable nuclear atypia were also seen, which were generated from B cells.
CONCLUSIONSThe main CT findings of pulmonary MALT lymphoma include nodules, mass or patchy consolidations with air brochogram; hilar and mediastinal lymphadenopathies are rare. Clinical diagnosis should also be based on pathological findings and immunohistochemical results.