Advances in syphilis detection.
- Author:
Jun LI
1
;
He-Yi ZHENG
Author Information
1. Department of Dermatology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
- Publication Type:Journal Article
- MeSH:
Antigens, Bacterial;
blood;
Humans;
Immunoglobulin M;
blood;
Polymerase Chain Reaction;
methods;
Sensitivity and Specificity;
Syphilis;
blood;
diagnosis;
Syphilis Serodiagnosis;
Treponema pallidum;
immunology;
isolation & purification
- From:
Acta Academiae Medicinae Sinicae
2012;34(1):95-98
- CountryChina
- Language:Chinese
-
Abstract:
Syphilis, a chronic bacterial infection caused by the spirochete Treponema pallidum subsp. pallidum, remains a public health concern worldwide. Syphilis control is largely dependent upon early identification and prompt treatment. The diagnosis of syphilis is mainly based on laboratory tests, especially serology and dark-field microscopy. In recent years, recombinant Treponema pallidum antigen-based rapid tests, polymerase chain reaction, and immunoglobulin M antibody detection have also shown certain sensitivities and specificities for syphilitic patients at different stages.