Roles of Rho-associated coiled-coil protein kinase in multiple cell behaviors.
10.3881/j.issn.1000-503X.2012.03.018
- Author:
Dong LIU
1
;
Xing-yun CHEN
;
Yuan-guo ZHOU
Author Information
1. State Key Laboratory of Trauma, Burn, and Combined Injury, Molecular Biology Center, Research Instituteof Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, China.
- Publication Type:Journal Article
- MeSH:
Cell Division;
Cell Movement;
Cytoskeleton;
metabolism;
Humans;
rho-Associated Kinases;
metabolism;
physiology
- From:
Acta Academiae Medicinae Sinicae
2012;34(3):276-280
- CountryChina
- Language:English
-
Abstract:
Rho-associated coiled-coil protein kinase (ROCK) is a serine/threonine kinase that belongs to AGC family of kinases. By inducing the formation of stress fibers and reorganizing the cytoskeleton, it is involved in many biological behaviors of cells including cell contraction, cell migration, cell division, and morphological changes, and thus exerts important roles in regulating the multiple functions of cells.