A Conjunctival Malignant Melanoma Involving the Cornea.
- Author:
Jung Sig MOON
1
;
Ja Young LEE
;
Sung Kun CHUNG
;
Young Suk YU
Author Information
1. Department of Ophthalmology, School of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Conjunctival malignant melanoma;
Fontana-Masson stain;
HMB 45 stain;
S-100 protein stain
- MeSH:
Adult;
Citric Acid;
Cornea*;
Epithelium;
Humans;
Magnetic Resonance Imaging;
Male;
Melanins;
Melanoma*;
Neoplasm Metastasis;
Orbit;
S100 Proteins;
Ultrasonography
- From:Journal of the Korean Ophthalmological Society
1998;39(6):1035-1039
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In a case of conjunctival malignant melanoma involving the cornea, we evaluated the findings of H,E, Fontana-Masson, S-100 protein, HMB 45 stain after the localized excision in 39 years old male patient. B-scan ultrasonography, orbit, MRI, Ga citrate scanning and bone scan showed no metastasis to the intraocular tissue, orbital adnexae and other organs. In H-E stain, spindle cells containing melanin pigment which was growing diffusely underneath the conjunctival epithelium could be seen. Fontana-Masson and S-100 protein staining resulted in diffusely positive findings, Therefore we could diagnose as 8 spindle B type malignant m.elanom.a. By histopathological examination, in a case of confirmed spindle B type COunctival malignant melanoma involving the cornea, good result, could be obtained by localized excision followed by 11 months.
