Clinical Analysis of Penetrating Keratoplasty in Herpes Simplex Keratitis.
- Author:
Jong Suk JEONG
1
;
Tae Hwa OH
;
Nam Ju MOON
Author Information
1. Department of Ophthalmology, National Medical Center, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Herpes simplex keratitis;
Penetrating Keratoplasty;
Recurrence;
Rejection
- MeSH:
Corneal Opacity;
Follow-Up Studies;
Graft Rejection;
Herpes Simplex*;
Humans;
Keratitis, Herpetic*;
Keratoplasty, Penetrating*;
Recurrence;
Retrospective Studies
- From:Journal of the Korean Ophthalmological Society
1998;39(6):1111-1118
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We conducted a retrospective study of 20 penetrating keratoplasty (19patients) for corneal opacity due to herpes simplex keratitis from January 1992 to February 1997 at National Medical Center. We exaniined f requeuey of graft rejection and recurrence of herpetic keratitis after penetrating keratoplasty. The patients were grouped into control & treatinent, group according to the use of antivirial drug after penetrating keratoplasty and we examined the difference in rate of recurrence between two groups. The follow-up period was from 8 months to 68 months, mean follow-up period being 29.6 months. Graft rejection was seen in 3 eyes out of 20 eyes (15.0%) and recurrence was developed 3 eyes out of 20 eyes (15.0%). Recurrent herpetic keratitis developed in 15.4%(2 of 13) of the eyes in control group and 14.3% (1 of 7) of the eyes in treatment group. There was no statistically significant difference in recurrence rate between two groups (p)0.05). Postoperative prophylactic antiviral treatment is not associated with decreased rate of herpes simplex keratitis recurrence.
