Exploration of the pathogenesis and the management of hypernatremia in burn patients.
- Author:
Shi-an YUAN
1
;
Xiao-dong YANG
;
Hong ZHANG
;
Cai-yun YANG
;
Rong XIAO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Blood Glucose; metabolism; Blood Urea Nitrogen; Burns; blood; complications; mortality; Female; Humans; Hypernatremia; etiology; mortality; therapy; Infection; complications; Male; Middle Aged; Survival Rate; Treatment Outcome
- From: Chinese Journal of Burns 2004;20(1):40-42
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the pathogenesis and the management of hypernatremia in burn patients.
METHODSTwenty eight burn patients with hypernatremia were enrolled in the study and were divided into infection and non-infection groups. The pathogenesis, clinical features, biochemical indices in blood, the therapeutic results and the prognosis were compared between the two groups.
RESULTSIn non-infection group, the hypernatremia was mainly induced by improper fluid resuscitation and occurred on the 3.1 postburn day (PBD), while that in the infected group, on 7.2 PBD. The patients in non-infected group exhibited much more excited and the blood levels of glucose and urea nitrogen (BUN) were obviously decreased when compared with those in the infected group (P < 0.01). The survival rate in non-infected and infected group were 94.12% and 9.09%, respectively.
CONCLUSIONThe mortality rate of the patients with hypernatremia could be lowered by means of taking optimal measures according to the different patterns of hypernatremia.