Potential applications of beta-elemene in anti-atherosclerosis and anti-restenosis.
- Author:
Qinglei DONG
1
;
Tieying YIN
;
Guixue WANG
Author Information
1. Key Laboratory of Biorheological Science and Technology, Ministry of Education, Chongqing Engineering Laboratory in Vascular Implants, Bioengineering College of Chongqing University, Chongqing 400044, China.
- Publication Type:Journal Article
- MeSH:
Anti-Inflammatory Agents;
pharmacology;
Antioxidants;
pharmacology;
Atherosclerosis;
prevention & control;
Coronary Restenosis;
prevention & control;
Humans;
Sesquiterpenes;
pharmacology
- From:
Journal of Biomedical Engineering
2013;30(3):656-660
- CountryChina
- Language:Chinese
-
Abstract:
It is well known that beta-elemene is a broadly effective antitumor drug. In recent years, many studies suggested that beta-elemene also has potential value in the treatment of atherosclerosis and restenosis. In this paper, the effect of beta-elemene in inhibition of angiogenesis, inhibition of thrombus formation, improvement of hemorheology, protection against oxidative injuries, anti-inflammation and suppression of restenosis after percutaneous transluminal coronary angioplasty (PTCA) are summarized and reviewed.
