Diagnostic value of left ventricular function after adenosine loading detected by gated myocardial perfusion imaging for prediction of major adverse cardiac events.
- Author:
Lisha JIANG
1
;
Xiaohong OU
1
;
Rui HUANG
1
;
Zhongzhi QI
1
;
Qinping FAN
1
;
Lin LI
1
Author Information
1. Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
- Publication Type:Journal Article
- MeSH:
Adenosine;
Aged;
Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography;
methods;
Coronary Disease;
diagnostic imaging;
physiopathology;
Female;
Humans;
Male;
Middle Aged;
Prognosis;
Tomography, Emission-Computed, Single-Photon;
methods;
Ventricular Function, Left;
physiology
- From:
Journal of Biomedical Engineering
2013;30(5):1003-1006
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to analyze the value of the SPECT MPI to myocardial ischemia and cardiac function parameters in the CAD prognosis assessment. A total of 890 patients with suspected CAD underwent adenosine loading stress gated SPECT. At a mean follow-up of (2.3 +/- 0. 4) year, a total of 37 adverse events occurred, including 12 cardiac deaths and 25 nonfatal myocardial infarctions. Univariate Cox analysis showed that diabetes (wald 6.95, P < 0.01), SSS (wald 24.31, P < 0.001), EF (wald 17.14, P < 0.001), ESV (wald 8.58, P < 0.01) and EDV (wald 7.95, P < 0.01) were significant predictors of MACEs. Multivariate Cox analysis showed that SSS (wald 6.69, P < 0.05) and EF (wald 4.70, P < 0.05) were independent predictors. According to the results, SSS and EF are both independent predictors of MACEs.
