Investigation on free circulating toxin in the blood of tetanus patients
- Author:
Ha Dang Le
- Publication Type:Journal Article
- Keywords:
tetanus
- MeSH:
Tetanus;
Bood
- From:Journal of Preventive Medicine
2002;12(1):18-22
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
79 sera of tetanus patients (Institute for Clinical Research in Tropical Diseases 1966, 1967, 1996 to 1997 were investigated for circulating toxin, using the mouse inoculation technique). Results: free circulating tetanus toxin was detected in 19,0% cases, among them 5,1% had low toxic concentration and 13,9% had high toxic concentration. The presence of free circulating tetanus toxin in the blood was not related to the infectious condition of the wound at admission. The mortality in the group with positive free circulating tetanus toxic was higher 60% than this in the negative one. So the presence of free circulating tetanus toxin in the blood had a prognostic value in tetanus patients. The use of tetanus antitoxin was necessary in the treatment of tetanus patients to neutralize free circulating tetanus toxin.
