Comparative study on effects of static pressure stimulation on release of PGE2 and IL-6 in fibroblasts in the rat "Zusanli" and its adjacent areas.
- Author:
Bo CHEN
1
;
Yong-Fen LUO
;
Jin CUI
;
Ling-Mei FENG
;
Xiao-Fang YANG
;
Lin FENG
Author Information
- Publication Type:Journal Article
- MeSH: Acupressure; Acupuncture Points; Animals; Dinoprostone; secretion; Fascia; cytology; Fibroblasts; secretion; Interleukin-6; secretion; Male; Rats; Rats, Sprague-Dawley; Signal Transduction; physiology
- From: Chinese Acupuncture & Moxibustion 2007;27(2):135-140
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo provide some possible theoretical and experimental basis for the modern biomedical mechanism of "receiving stimulation, preventing and treating diseases", by exploring the effects of pressure signal's biological transformation of rat "Zusanli" (ST 36) fascia tissue fibroblasts under mechanical stimulation.
METHODSPressure was given on rat "Zusanli" (ST 36) and its adjacent area's fascia tissue cells cultured in vitro and identified by morphology. The contents of prostaglandin E2 (PGE2) and interleukin-6 (IL-6) in culture medium were detected.
RESULTSThe fascia tissue cells in "Zusanli" and its adjacent area are almost consisted of fibroblasts. The pressure stimulation significantly accelerated the synthesis and release of PGE2 and IL-6.
CONCLUSIONAcupoint and non-acupoint fibroblasts can directly receive mechanical stimulation, and then the mechanical signals were transformed as biological ones.
