Effects and comparison of seed oil and sarcocarp oil of Hippophae rhamnoides on rats with experimental hepatocirrhosis.
- Author:
Chao LIU
1
;
Jing XU
;
Cun-qi YE
;
Cheng HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Alanine Transaminase; blood; Animals; Carbon Tetrachloride Poisoning; Drugs, Chinese Herbal; isolation & purification; pharmacology; Fruit; chemistry; Hippophae; chemistry; Liver; enzymology; Liver Cirrhosis, Experimental; etiology; metabolism; Male; Plant Oils; isolation & purification; pharmacology; Plants, Medicinal; chemistry; Rats; Seeds; chemistry; Superoxide Dismutase; metabolism
- From: China Journal of Chinese Materia Medica 2006;31(13):1100-1102
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEA study was carried out to investigate the effects of seed oil and sarcocarp oil of Hippophae rhamnoides on rats with experimental hepatocirrhosis, and comparison between the two.
METHODA rat model of experimental hepatocirrhosis was set up by feeding CCl4. Different concentration of seed oil and sarcocarp oil of H. rhamnoides were feed to those rats for 45 d, then the changes of activity of ALT in serum and SOD in liver were measured.
RESULTBoth of seed oil and sarcocarp oil can control the increase of ALT in serum and the decrease of SOD evidently, and the effect of seed oil was turn out to be a little better than sarcocarp oil.
CONCLUSIONSeed oil was more effective than sarcocarp oil of H. rhamnoides in alleviating liver injury caused by CCl4.
