Affection of Bushen Shengjing pill on NO and NOS in testicle and ante-oxidization of rat with spermatogenic cell injury.
- Author:
A-min YANG
1
;
Yue-qing LI
;
Hai-song LI
;
Chong-shun SONG
;
Ying REN
;
Jun-xiang YIN
Author Information
- Publication Type:Journal Article
- MeSH: Adenine; Animals; Drug Combinations; Drugs, Chinese Herbal; isolation & purification; pharmacology; Fertility Agents, Male; pharmacology; Kidney Diseases; chemically induced; metabolism; Male; Malondialdehyde; metabolism; Nitric Oxide; metabolism; Nitric Oxide Synthase; metabolism; Plants, Medicinal; chemistry; Random Allocation; Rats; Rats, Sprague-Dawley; Spermatogenesis; drug effects; Superoxide Dismutase; metabolism; Testis; metabolism; Yang Deficiency; chemically induced; metabolism
- From: China Journal of Chinese Materia Medica 2006;31(11):904-906
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEDiscuss the functional mechanism of treating male infertility with Bushen Shengjing pill (BS).
METHODFill the SD rat with adenine so as to injure the germ cell which will produce the model rat with kidney yang deficiency. Measure the activity of SOD and NOS, the amount of NO and MDA in the testicle.
RESULTBS can promote the activity of SOD, reduce the activity of NOS and the amount of NO and MDA.
CONCLUSIONBS has the function of protecting the germ cell which is closely related to the function that the pill can promote the activity of SOD, reduce the activity of NOS and the amount of NO and MDA.
