Study on application of activated carbon in paclitaxel injection.
- Author:
Li LIU
1
;
Jia-bo LUO
;
Xue-feng XING
Author Information
- Publication Type:Journal Article
- MeSH: Antineoplastic Agents, Phytogenic; administration & dosage; Charcoal; administration & dosage; analysis; Drug Compounding; methods; Injections; Paclitaxel; administration & dosage; Quality Control; Temperature
- From: China Journal of Chinese Materia Medica 2006;31(9):735-736
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo inspect the effect of activated carbon with different dosage and temperature on quality of paclitaxel injection.
METHODDeterminations in WS1-(X-026)-2001Z-paclitaxel injection were refered to compare the effect of different dosage and temperature for activated carbon on the taxol content, related material, clarity and bacterial endotoxin.
RESULTWhen used with 0.25% and 35 degrees C, activated carbon will ensure the quality of paclitaxel injection.
CONCLUSION0.25% and 35 degrees C are the best condition when activated carbon is used in paclitaxel injection.
