Progress in metabolic engineering of microbial production of 1,3-dihydroxyacetone.
- Author:
Lihui SUN
1
;
Zhongce HU
;
Yuguo ZHENG
;
Yinchu SHEN
Author Information
1. Institute of Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China.
- Publication Type:Journal Article
- MeSH:
Dihydroxyacetone;
biosynthesis;
Fermentation;
Genetic Engineering;
methods;
Gluconobacter oxydans;
genetics;
metabolism;
Industrial Microbiology;
methods;
Metabolic Engineering;
methods;
Sugar Alcohol Dehydrogenases;
metabolism
- From:
Chinese Journal of Biotechnology
2010;26(9):1218-1224
- CountryChina
- Language:Chinese
-
Abstract:
1,3-Dihydroxyacetone is widely used in cosmetics, medicines and food products. We reviewed the recent progress in metabolic pathways, key enzymes, as well as metabolic engineering for microbial production of 1,3-dihydroxyacetone. We addressed the research trend to increase yield of 1,3-dihydroxyacetone by improving the activity of glycerol dehydrogenase with genetic engineering, and regulating of fermentation process based on metabolic characteristic of the strain.
