Progress in metabolic mechanism of docosahexenoic acid production by fermentation.
- Author:
Yun FENG
1
;
Lujing REN
;
Ping WEI
;
Qianqian TONG
;
Xiaojun JI
;
He HUANG
Author Information
1. State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 210009, China.
- Publication Type:Journal Article
- MeSH:
Docosahexaenoic Acids;
biosynthesis;
Eukaryota;
metabolism;
Fermentation;
Industrial Microbiology;
methods;
Metabolic Engineering;
methods
- From:
Chinese Journal of Biotechnology
2010;26(9):1225-1231
- CountryChina
- Language:Chinese
-
Abstract:
Docosahexenoic acid (DHA) is an important polyunsaturated fatty acid which is beneficial to human health. Compared with the DHA derived from fish oil, DHA by microbial production possesses many advantages, and has a bright prospect. In this article, we reviewed strains, metabolic pathway, key enzymes and mechanism of lipid accumulation for microbial production of DHA. Those information would be greatly helpful for further improving DHA production by metabolic engineering.
