Recent progress of the research on spore surface display.
- Author:
Xiaoman XU
1
;
Xiaochen WANG
;
Cuiqing MA
Author Information
1. State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, China.
- Publication Type:Journal Article
- MeSH:
Bacillus subtilis;
genetics;
metabolism;
Biocatalysis;
Biotechnology;
methods;
Gene Expression Regulation, Bacterial;
Genetic Engineering;
methods;
Recombinant Proteins;
genetics;
metabolism;
Spores, Bacterial;
genetics;
metabolism;
Tetanus Toxoid;
genetics;
immunology
- From:
Chinese Journal of Biotechnology
2010;26(10):1404-1409
- CountryChina
- Language:Chinese
-
Abstract:
Spore surface display is one of attractive microorganism surface display systems. With the advantage of resistance attribute and specific assembly pattern, the technology of spore surface display now is attracting more and more attention. According to the current reports and main achievements of spore surface display, the structure and assembly of spores, the principle for construction and some existing spore surface display systems were elaborated in this paper. Now with the unique property of spores, the technique is not only widely used in production of vaccines but also has great applied potential in the field of biocatalysis and cell-factory.
