Microbial cell factories for production of polyhydroxyalkanoates.
- Author:
Zhengjun LI
1
;
Xiaoxing WEI
;
Guoqiang CHEN
Author Information
1. School of Life Sciences, Tsinghua University, Beijing 100084, China.
- Publication Type:Journal Article
- MeSH:
Bacteria;
metabolism;
Genetic Engineering;
Industrial Microbiology;
Metabolic Networks and Pathways;
Polyhydroxyalkanoates;
biosynthesis;
chemistry;
genetics
- From:
Chinese Journal of Biotechnology
2010;26(10):1426-1435
- CountryChina
- Language:Chinese
-
Abstract:
Polyhydroxyalkanoates (PHA) are diverse polyesters synthesized by a variety of bacteria as intracellular carbon and energy storage compounds. As bio-renewable and biodegradable materials with diverse properties, PHA have drawn industrial attentions for their potential applications in many fields. This review focuses on recent strain developments for PHA production via cofactor engineering and metabolic engineering. The microaerobic production of PHA and application of PHA synthesis genes for improving robustness of industrial microorganisms are addressed.
