Effects of physical environments on nucleation of protein crystals: a review.
- Author:
Ruiqing CHEN
1
;
Jun LIU
;
Qinqin LU
;
Yongming LIU
;
Dachuan YIN
Author Information
1. Key Laboratory for Space Bioscience & Biotechnology, School of Life Sciences, Northwestern Polytechnic University, Xi'an 710072, China.
- Publication Type:Journal Article
- MeSH:
Crystallization;
Crystallography, X-Ray;
Electromagnetic Fields;
Environment;
Light;
Protein Conformation;
Proteins;
chemistry;
Temperature
- From:
Chinese Journal of Biotechnology
2011;27(1):9-17
- CountryChina
- Language:Chinese
-
Abstract:
This paper reviews the effects of physical environments (including light, electric field, ultrasound, magnetic field, microgravity, temperature, mechanical vibration, and heterogeneous nucleation interface) on protein crystal nucleation. The research results are summarized and the possible mechanisms of the effects are discussed. In the end of this review, the application prospects of these physical environments (including coupled environments) in protein crystallization are presented.
