Primary Adenosquamous Cell Carcinoma of the Pancreas: A Case Report with a Review of the Korean Literature.
10.3904/kjim.2011.26.3.348
- Author:
Youn Ju NA
1
;
Ki Nam SHIM
;
Min Sun CHO
;
Sun Hee SUNG
;
Sung Ae JUNG
;
Kwon YOO
;
Kyu Won CHUNG
Author Information
1. Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea. kwchung@ewha.ac.kr
- Publication Type:Case Report ; Review
- Keywords:
Pancreas;
Carcinoma, Adenosquamous
- MeSH:
Amylases/blood;
Biopsy, Fine-Needle;
CA-19-9 Antigen/blood;
Carcinoma, Adenosquamous/blood/complications/*diagnosis/pathology;
Duodenoscopy;
Duodenum/pathology;
Humans;
Intestinal Mucosa/pathology;
Lipase/blood;
Male;
Middle Aged;
Neoplasm Invasiveness;
Pancreatic Neoplasms/blood/complications/*diagnosis/pathology;
Tomography, X-Ray Computed
- From:The Korean Journal of Internal Medicine
2011;26(3):348-351
- CountryRepublic of Korea
- Language:English
-
Abstract:
The most common pancreatic cancer is adenocarcinoma. Primary adenosquamous cell carcinoma of the pancreas is very rare and aggressive. A 46-year-old man presented with a 3-month history of dyspepsia and a 7-kg weight loss. The physical examination showed tenderness of the right upper quadrant of the abdomen. There was no jaundice. Amylase and lipase were elevated. CA 19-9 was elevated to 566.7 U/mL. Gastroduodenoscopy showed a hard ulceroinfiltrative mass with a yellowish exudate that bled readily on touch in the second portion of the duodenum. Abdominal computed tomography showed a 7.1 x 6.3-cm heterogeneously enhancing mass in the pancreatic head. The pancreatic mass had invaded the duodenum wall, gastric antrum, and gastroduodenal artery sheath. Fine-needle aspiration biopsy of the pancreatic mass revealed adenosquamous cell carcinoma, anaplastic type. We concluded that an adenosquamous cell carcinoma of pancreas had invaded the duodenal mucosa causing ulceration.
