Acute Generalized Exanthematous Pustulosis Due to Oral Use of Blue Dyes.
10.3904/kjim.2011.26.3.360
- Author:
Osman SENER
1
;
Osman KOSE
;
Ozgur KARTAL
;
Mukerrem SAFALI
Author Information
1. Division of Allergy, Department of Internal Medicine, Gulhane Military Medical Academy and Medical School, Ankara, Turkey. drozkartal@hotmail.com
- Publication Type:Case Report
- Keywords:
Methylene blue;
Indigofera;
Drug eruptions
- MeSH:
Acute Generalized Exanthematous Pustulosis/*chemically induced/drug therapy/pathology;
Administration, Oral;
Adrenal Cortex Hormones/therapeutic use;
Aged;
Biopsy;
Coloring Agents/administration & dosage/*adverse effects;
Humans;
Indoles/administration & dosage/*adverse effects;
Intradermal Tests;
Male;
Methylene Blue/administration & dosage/*adverse effects;
Skin/*drug effects/pathology;
Treatment Outcome
- From:The Korean Journal of Internal Medicine
2011;26(3):360-363
- CountryRepublic of Korea
- Language:English
-
Abstract:
Acute generalized exanthematous pustulosis is a rare severe pustular cutaneous adverse reaction characterized by a rapid clinical course with typical histological findings. It is accompanied by fever and acute eruption of non-follicular pustules overlying erythrodermic skin. The causative agents are most frequently antibacterial drugs. We present a patient with acute generalized exanthematous pustulosis caused by methylene blue and indigotin dyes.