Risk factors for poor prognosis in children with severe adenovirus pneumonia.
- Author:
Miao HUANG
1
;
Rong LUO
;
Zhou FU
Author Information
- Publication Type:Journal Article
- MeSH: Adenoviridae Infections; complications; Adolescent; Child; Child, Preschool; Female; Humans; Infant; Logistic Models; Male; Pneumonia, Viral; complications; Prognosis; Retrospective Studies; Risk Factors; Serum Albumin; analysis
- From: Chinese Journal of Contemporary Pediatrics 2017;19(2):159-162
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the risk factors for poor prognosis of severe adenovirus pneumonia (SAP) in children.
METHODSThe clinical data of 189 children with SAP were retrospectively analyzed. Univariate logistic regression analysis was performed to assess the risk factors for poor prognosis.
RESULTSThe univariate logistic regression analysis showed that the patients with hemoglobin <90 g/L, plasma albumin <30 g/L, C-reactive protein >30 mg/L, procalcitonin >10 ng/mL, alanine aminotransferase >100 U/L, or aspartate aminotransferase >100 U/L had poor prognosis (P<0.05), and that those with congenital dysplasia of the airway, acute respiratory distress syndrome, circulatory complications, electrolyte and acid-base disturbance, or more than three complications also had poor prognosis (P<0.05).
CONCLUSIONSPoor prognosis of severe adenovirus pneumonia in children is associated with anemia, low serum albumin, inflammatory response, concurrent multiple complications and underlying lung diseases.