Risk factors for allergic diseases in children aged 0-24 months in the Wuhu urban area, Anhui Province, China.
- Author:
Shou-Gui WANG
1
;
Xiang-Sheng ZHANG
;
Yan-Fang ZHAO
;
Li SUN
;
Xi-Tao PAN
;
Ning WAN
Author Information
- Publication Type:Journal Article
- MeSH: Child, Preschool; Female; Humans; Hypersensitivity; etiology; Infant; Infant, Newborn; Logistic Models; Male; Risk Factors
- From: Chinese Journal of Contemporary Pediatrics 2017;19(3):303-307
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the prevalence of allergic diseases in children aged 0-24 months in the Wuhu urban area of Anhui Province and risk factors for allergic diseases.
METHODSCluster random sampling was performed to select 600 children aged 0-24 months and their mothers from the Wuhu urban area, and a questionnaire survey was conducted to collect the data of disease history, family history, mothers' conditions during pregnancy, and child-rearing situation. Univariate analysis and multivariate logistic regression analysis were performed for such data.
RESULTSAmong the 597 children included in the analysis, 56 (9.4%) were diagnosed with allergic diseases in the past. The univariate analysis showed that the age, use of antipyretic and analgesic drugs, a history of allergy in the father or grandparents, and the consumption of fish, shrimps, crabs, and shellfish during pregnancy were significantly associated with past allergic diseases (P<0.05). The multivariate logistic regression analysis showed that the age and a history of allergy in the father or grandparents were positively associated with past allergic diseases (OR=4.0-4.9, 2.7, and 2.4 respectively; P<0.05), while frequent consumption of fish, shrimps, crabs, and shellfish during pregnancy was negatively associated with past allergic diseases (OR=0.3; P<0.05).
CONCLUSIONSA family history of allergy is an independent risk factor for allergic diseases in children aged 0-24 months in the Wuhu urban area of Anhui Province, while frequent consumption of fish, shrimps, crabs, and shellfish during pregnancy is a protective factor.