Study on professor Yan Zhenghua's medication regularity in treating heart diseases based on association rules and entropy cluster.
- Author:
Jia-rui WU
;
Wei-xian GUO
;
Xiao-meng ZHANG
;
Bing ZHANG
;
Yue ZHANG
- Publication Type:Journal Article
- MeSH:
Drug Interactions;
Drug Therapy, Combination;
Drugs, Chinese Herbal;
chemistry;
history;
therapeutic use;
Entropy;
Heart Diseases;
drug therapy;
history;
History, 20th Century;
History, 21st Century;
Humans
- From:
China Journal of Chinese Materia Medica
2015;40(8):1601-1604
- CountryChina
- Language:Chinese
-
Abstract:
In this study, Professor Yan Zhenghua's recipes for treating heart diseases were collected to determine the frequency and association rules among drugs by such data mining methods as apriori algorithm and complex system entropy cluster and summarize Pro- fessor Yan Zhenghua's medication experience in treating heart diseases. The results indicated that frequently used drugs included Salviae Miltiorrhizae Radix et Rhizoma, Parched Ziziphi Spinosae Semen, Polygoni Multiflori Caulis, Ostreae Concha, Poria; frequently used drug combinations included "Ostreae Concha, Draconis Os", "Polygoni Multiflori Caulis, Parched Ziziphi Spinosae Semen" , and "Salviae Miltiorrhizae Radix et Rhizoma, Parched Ziziphi Spinosae Semen". The drug combinations with the confidence of 1 included "Dalbergiae Odoriferae Lignum-->Salviae Miltiorrhizae Radix et Rhizoma", "Allii Macrostemonis Bulbus-->Parched Ziziphi Spinosae Semen", "Draconis Os-->Ostreae Concha", and "Salviae Miltiorrhizac Radix et Rhizoma, Draconis Os-->Ostreae Concha". The core drug combinations included" Chrysanthemi Flos-Gastrodiae Rhizoma-Tribuli Fructus", "Dipsaci Radix-Taxillus sutchuenensis-Achyranthis Bidentatae Radix", and "Margaritifera Concha-Polygoni Multiflori Caulis-Platycladi Semen-Draconis Os".
