Study on meridian tropism of medicinal property theory for Chines medicines by supramolecular chemistry (I).
- Author:
Fu-yuan HE
;
Kai-wen DENG
;
Yan-tao YANG
;
Yi-qun ZHOU
;
Ji-lian SHI
;
Wen-long LIU
;
Yu TANG
- Publication Type:Journal Article
- MeSH:
Acupuncture Points;
Drug Therapy;
Drugs, Chinese Herbal;
chemistry;
Humans;
Medicine, Chinese Traditional;
Meridians
- From:
China Journal of Chinese Materia Medica
2015;40(8):1624-1629
- CountryChina
- Language:Chinese
-
Abstract:
In this paper, based on the special influence of supramolecular chemistry on the basic theory of Chinese medicines ( CM) , the authors further analyzed the history of meridian tropism and natural origins of CM organisms and explained CM ingredients and the universal regularity of the automatic action of the supramolecular "imprinting templates" hole channel structure. After entering human bodies, CMs, as the aggregation of supramolecular "imprinting templates" , automatically seek supramolecular subjects that are matched with their "imprinting templates" in human meridians and organs for the purpose of self-recognition, self-organization, self-assembly and self-replication, so as to generate specific efficacy in meridians and organs, which is reflected as the meridian tropism phenomena at macro level. This regularity can be studied by in vitro and in vivo experimental studies. In vitro methods are mostly supra molecular structure analysis and kinetic and thermodynamic parameter calculation; Whereas in vivo methods are dominated by the analysis on object component distribution, chromatopharmacodynamic parameters and network chromatopharmacodynamic parameters; Particularly, the acupoint-medicine method can simplify to study the supramolecular subject-object relations. Consequently, CM's'meridian tropism reveals the universal regularity for interactions of macromolecular and micromolecular "imprinting templates" of subjects and objects in natural organisms. As the first barrier for the material base of the CM theory and breakthrough in the modernization of the basic CM theory, meridian tropism plays an important role in studies on basic theories of the basic CM theory.
