Application of adipose-derived stem cells in lower urinary tract reconstruction.
- Author:
Zhe ZHOU
1
;
Ming ZHANG
;
Mu-Jun LU
Author Information
1. Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China.
- Publication Type:Journal Article
- MeSH:
Adipocytes;
cytology;
Humans;
Stem Cells;
cytology;
Tissue Engineering;
Urinary Tract;
surgery
- From:
National Journal of Andrology
2013;19(4):365-369
- CountryChina
- Language:Chinese
-
Abstract:
Adipose-derived stem cells have self-renewal and multi-differentiation potentials, which can differentiate into smooth muscle cells, urinary epithelial-like cells, endothelial cells, neuron-like cells, etc. and secrete a variety of growth factors. As a result, the research on adipose-derived stem cells in lower urinary tract reconstruction using tissue engineering has been a highlight in recent years. This review focuses on the application of adipose-derived stem cells as seed cells to lower urinary tract reconstruction by tissue engineering in such diseases as bladder defect, stress urinary incontinence, and erectile dysfunction.
