Tadalafil combined with behavior therapy for semen collection from infertile males in whom masturbation fails.
- Author:
Wen-Hao TANG
1
;
Hui JIANG
;
Lu-Lin MA
;
Kai HONG
;
Lian-Ming ZHAO
;
De-Feng LIU
;
Jia-Ming MAO
;
Yi YANG
;
Ju ZHANG
;
Ling GAO
;
Jie QIAO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Behavior Therapy; Carbolines; therapeutic use; Humans; Male; Masturbation; therapy; Middle Aged; Semen; Tadalafil; Treatment Failure; Treatment Outcome
- From: National Journal of Andrology 2013;19(5):439-442
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of Tadalafil combined with behavior therapy in helping obtain semen from infertile men in whom masturbation has failed.
METHODSSixty male infertile patients from whom masturbation had failed to obtain semen were equally assigned to receive Tadalafil combined with behavior therapy (combination group) or Tadalafil only (control group). All the patients took Tadalafil 20 mg orally the night before the day of semen collection by masturbation. Before this procedure, the patients of the combination group practiced masturbation 16 - 24 times at home.
RESULTSThe average ages of the patients were (37.0 +/- 5.1) yr and (37.5 +/- 5.2) yr and their IIEF-5 scores were 16.50 +/- 1.25 and 16.90 +/- 1.09 in the combination and the control group, respectively, neither with statistically significant difference between the two groups. Semen was successfully obtained from 9 patients (30.0%) of the combination group and 1 patient (3.33%) of the control group, with statistically significant difference between the two groups (chi2 = 7.680, P < 0.01).
CONCLUSIONBy training the patients and establishing a conditioned response to masturbation, Tadalafil combined with behavior therapy can significantly increase the success rate of semen collection from the male infertile patients in whom masturbation fails.