Heat shock protein in male infertility: advances in studies.
- Author:
Ben HE
1
;
Qiang LI
;
Hui ZHUO
Author Information
1. Department of Urology, Chengdu Second School of Clinical Medicine of Chongqing Medical University/The Third People's Hospital of Chengdu, Chengdu, Sichuan 610031, China. outlookhb@126.com
- Publication Type:Journal Article
- MeSH:
Heat-Shock Proteins;
metabolism;
Humans;
Infertility, Male;
metabolism;
Male;
Spermatozoa;
metabolism
- From:
National Journal of Andrology
2013;19(5):464-467
- CountryChina
- Language:Chinese
-
Abstract:
Heat shock protein (HSP) is a group of evolutionarily highly conserved cell chaperone proteins involved in the processes of molecular chaperone, cytoprotection, anti-apoptosis and immunoregulation. Recent studies found that HSP is also involved in spermatogenesis, sperm capacitation and fertilization, which play a significant role in male reproduction. Therefore, further studies on the action mechanisms of HSP in male infertility may offer a new insight into the management of the problem.
